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A brief summary of myself

I am a researcher at the University of Edinburgh, where I utilize state-of-the-art statistical models to study Major Depressive Disorder. My expertise lies in the intersection of neuroscience and genomics, a field known as neuro-genomics. With a strong interest in mental health disorders, I believe it is crucial to combine these two disciplines to uncover the true mechanisms underlying depression. In my >7 years of research in mental health conditions, I analyse large-scale clinical data to investigate the biological mechanisms. This involves statistical programming, data visualization, and writing research articles. I strongly believe in the power of data and figures, and I strive to conduct data-driven research.
 
 
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Education

  • 2015-2019: PhD in Psychiatry, University of Edinburgh, UK
  • 2012-2015: MSc in Cognitive Neuroscience, Beijing Normal University, China
  • 2008-2012: BSc in Psychology, South China Normal University, China
 

Work

  • 2019-2023: Research Fellow, University of Edinburgh
  • 2010-2010: On-campus counsellor, Zhaoqing High School, China
 

Publication

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Number of first/corresponding author publications: 9 Total number of peer-reviewed publications: 54 (total citation = 3,910)
Research articles (click here to see the full list)
  1. First/corresponding-author publications:
  1. Shen, X.*, Caramaschi, D., Adams, M. J., Walker, R. M., Min, J. L., Kwong, A., Hemani, G., Consortium, G. o. D. M., Barbu, M. C., . . . Whalley, H. C. (2022). DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses. Genome Medicine 14(1), 36.
  1. Thng, G., Shen, X.* (corresponding author), Stolicyn, A., Harris, M. A., Adams, M. J., Barbu, M. C., Kwong, A. S., Frangou, S., Lawrie, S. M., . . . McIntosh, A. M. (2022). Comparing personalized brain-based and genetic risk scores for major depressive disorder in large population samples of adults and adolescents. European Psychiatry 65(1), e44.
  1. Shen, X.*, MacSweeney, N., Chan, S. W., Barbu, M. C., Adams, M. J., Lawrie, S. M., Romaniuk, L., McIntosh, A. M., & Whalley, H. C. (2021). Brain structural associations with depression in a large early adolescent sample (the ABCD study®). EClinicalMedicine 42.
  1. Shen, X.*, Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T.-K., Deary, I. J., Whalley, H. C., & McIntosh, A. M. (2020). A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank. Nature Communications 11(1), 2301.
  1. Shen, X.*, Adams, M. J., Ritakari, T. E., Cox, S. R., McIntosh, A. M., & Whalley, H. C. (2019). White matter microstructure and its relation to longitudinal measures of depressive symptoms in mid-and late life. Biological Psychiatry 86(10), 759-768.
  1. Shen, X.*, Cox, S. R., Adams, M. J., Howard, D. M., Lawrie, S. M., Ritchie, S. J., Bastin, M. E., Deary, I. J., McIntosh, A. M., . . . Whalley, H. C. (2018). Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 3(10), 878-886.
  1. Shen, X.*, Reus, L. M., Cox, S. R., Adams, M. J., Liewald, D. C., Bastin, M. E., Smith, D. J., Deary, I. J., Whalley, H. C., . . . McIntosh, A. M. (2017). Subcortical volume and white matter integrity abnormalities in major depressive disorder: findings from UK Biobank imaging data. Scientific reports 7(1), 5547.
  1. Zhu, R., Shen, X.*, Tang, H., Ye, P., Wang, H., Mai, X., & Liu, C. (2017). Self-punishment promotes forgiveness in the direct and indirect reciprocity contexts. Psychological reports 120(3), 408-422.
  1. Shen, X.*, Mai, X., & Liu, C. (2015). Application of Internetbased big data in social cognitive science. Chinese Science Bulletin 60(11), 986-987.
Other peer-reviewed publications
  1. Bosma, M., Cox, S., Ziermans, T., Buchanan, C., Shen, X.*, Tucker-Drob, E., Adams, M., Whalley, H., & Lawrie, S. (2023). White matter, cognition and psychotic-like experiences in UK Biobank. Psychological Medicine 53(6), 2370-2379.
  1. Cullen, B., Gameroff, M. J., Ward, J., Bailey, M. E. S., Lyall, D. M., Lyall, L. M., MacSweeney, N., Murphy, E., Sangha, N., . . . Weissman, M. M. (2023). Cognitive Function in People With Familial Risk of Depression. JAMA Psychiatry 80(6), 610-620. https://doi.org/10.1001/jamapsychiatry.2023.0716
  1. Davyson, E., Shen, X.*, Gadd, D. A., Bernabeu, E., Hillary, R. F., McCartney, D. L., Adams, M., Marioni, R., & McIntosh, A. M. (2023). Metabolomic investigation of major depressive disorder identifies a potentially causal association with polyunsaturated fatty acids. Biological Psychiatry.
  1. Gao, C., Amador, C., Walker, R. M., Campbell, A., Madden, R. A., Adams, M. J., Bai, X., Liu, Y., Li, M., . . . Zeng, Y. (2023). Phenome-wide analyses identify an association between the parent-of-origin effects dependent methylome and the rate of aging in humans. Genome Biol 24(1), 117. https://doi.org/10.1186/s13059-023-02953-6
  1. MacSweeney, N., Allardyce, J., Edmondson-Stait, A., Shen, X.*, Casey, H., Chan, S. W. Y., Cullen, B., Reynolds, R. M., Frangou, S., . . . Whalley, H. C. (2023). The role of brain structure in the association between pubertal timing and depression risk in an early adolescent sample (the ABCD Study(R)): A registered report. Dev Cogn Neurosci 60, 101223. https://doi.org/10.1016/j.dcn.2023.101223
  1. Madden, R. A., Atkinson, K., Shen, X.*, Green, C., Hillary, R. F., Hawkins, E., Sage, E., Sandu, A. L., Waiter, G., . . . Whalley, H. C. (2023). Structural brain correlates of childhood trauma with replication across two large, independent community-based samples. Eur Psychiatry 66(1), e19. https://doi.org/10.1192/j.eurpsy.2022.2347
  1. Stolicyn, A., Lyall, L. M., Lyall, D. M., Høier, N., Adams, M. J., Shen, X., Cole, J. H., McIntosh, A. M., Whalley, H. C., . . . Smith, D. J. (in press). Comprehensive Assessment of Sleep Duration, Insomnia and Brain Structure within the UK Biobank Cohort. Sleep, preprint available at: https://doi.org/10.1101/2023.06.19.23291496
  1. Barbu, M. C., Harris, M., Shen, X.*, Aleks, S., Green, C., Amador, C., Walker, R., Morris, S., Adams, M., . . . Whalley, H. (2022). Epigenome-wide association study of global cortical volumes in generation Scotland: Scottish family health study. Epigenetics 17(10), 1143-1158. https://doi.org/10.1080/15592294.2021.1997404
  1. Barbu, M. C., Amador, C., Kwong, A. S. F., Shen, X.*, Adams, M. J., Howard, D. M., Walker, R. M., Morris, S. W., Min, J. L., . . . McIntosh, A. M. (2022). Complex trait methylation scores in the prediction of major depressive disorder. eBioMedicine 79, 104000. https://doi.org/10.1016/j.ebiom.2022.104000
  1. Edmondson-Stait, A. J., Shen, X.*, Adams, M. J., Barbu, M. C., Jones, H. J., Miron, V. E., Allardyce, J., Boardman, J. P., Lawrie, S. M., . . . McIntosh, A. M. (2022). Early-life inflammatory markers and subsequent psychotic and depressive episodes between 10 to 28 years of age. Brain, Behavior, & Immunity-Health 26, 100528.
  1. Gadd, D. A., Hillary, R. F., McCartney, D. L., Shi, L., Stolicyn, A., Robertson, N. A., Walker, R. M., McGeachan, R. I., Campbell, A., . . . Marioni, R. E. (2022). Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health. Nat Commun 13(1), 4670. https://doi.org/10.1038/s41467-022-32319-8
  1. Harris, M. A., Cox, S. R., De Nooij, L., Barbu, M. C., Adams, M. J., Shen, X.*, Deary, I. J., Lawrie, S. M., McIntosh, A. M., . . . Whalley, H. C. (2022). Structural neuroimaging measures and lifetime depression across levels of phenotyping in UK biobank. Translational Psychiatry 12(1), 157.
  1. Yeung, H., Shen, X.*, Stolicyn, A., de Nooij, L., Harris, M., Romaniuk, L., Buchanan, C., Waiter, G., Sandu, A.-L., . . . McNeil, C. (2022). Spectral clustering based on structural magnetic resonance imaging and its relationship with major depressive disorder and cognitive ability (vol 54, pg 6281, 2021). EUROPEAN JOURNAL OF NEUROSCIENCE 56(5), 4700-4700.
  1. Barbu, M. C., Shen, X.*, Walker, R. M., Howard, D. M., Evans, K. L., Whalley, H. C., Porteous, D. J., Morris, S. W., Deary, I. J., . . . Zeng, Y. (2021). Epigenetic prediction of major depressive disorder. Molecular Psychiatry 26(9), 5112-5123.
  1. Green, C., Stolicyn, A., Harris, M. A., Shen, X.*, Romaniuk, L., Barbu, M. C., Hawkins, E. L., Wardlaw, J. M., Steele, J. D., . . . Waiter, G. D. (2021). Hair glucocorticoids are associated with childhood adversity, depressive symptoms and reduced global and lobar grey matter in Generation Scotland. Translational Psychiatry 11(1), 523.
  1. Green, C., Shen, X.*, Stevenson, A. J., Conole, E. L., Harris, M. A., Barbu, M. C., Hawkins, E. L., Adams, M. J., Hillary, R. F., . . . Lawrie, S. M. (2021). Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder. Brain, behavior, and immunity 92, 39-48.
  1. Howard, D. M., Adams, M. J., Shirali, M., Clarke, T.-K., Marioni, R. E., Davies, G., Coleman, J. R., Alloza, C., Shen, X.*, . . . Barbu, M. C. (2021). Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways (vol 9, 1470, 2018). Nature Communications 12(1).
  1. Schoorl, J., Barbu, M. C., Shen, X.*, Harris, M. R., Adams, M. J., Whalley, H. C., & Lawrie, S. M. (2021). Grey and white matter associations of psychotic-like experiences in a general population sample (UK Biobank). Translational Psychiatry 11(1), 21.
  1. Sewell, M. D., Jiménez-Sánchez, L., Shen, X.*, Edmondson-Stait, A. J., Green, C., Adams, M. J., Rifai, O. M., McIntosh, A. M., Lyall, D. M., . . . Whalley, H. C. (2021). Associations between major psychiatric disorder polygenic risk scores and blood-based markers in UK biobank. Brain, behavior, and immunity 97, 32-41.
  1. Yeung, H. W., Shen, X.*, Stolicyn, A., De Nooij, L., Harris, M. A., Romaniuk, L., Buchanan, C. R., Waiter, G. D., Sandu, A. L., . . . McNeil, C. J. (2021). Spectral clustering based on structural magnetic resonance imaging and its relationship with major depressive disorder and cognitive ability. EUROPEAN JOURNAL OF NEUROSCIENCE 54(6), 6281-6303.
  1. Barbu, M. C., Spiliopoulou, A., Colombo, M., McKeigue, P., Clarke, T.-K., Howard, D. M., Adams, M. J., Shen, X.*, Lawrie, S. M., . . . McIntosh, A. M. (2020). Expression quantitative trait loci-derived scores and white matter microstructure in UK Biobank: a novel approach to integrating genetics and neuroimaging. Translational Psychiatry 10(1), 55.
  1. de Nooij, L., Harris, M. A., Adams, M. J., Clarke, T.-K., Shen, X.*, Cox, S. R., McIntosh, A. M., & Whalley, H. C. (2020). Cognitive functioning and lifetime major depressive disorder in UK Biobank. European Psychiatry 63(1), e28.
  1. Harris, M. A., Shen, X.*, Cox, S. R., Gibson, J., Adams, M. J., Clarke, T.-K., Deary, I. J., Lawrie, S. M., McIntosh, A. M., . . . Whalley, H. C. (2020). Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures. Psychological Medicine 50(10), 1653-1662.
  1. Heinze, K., Shen, X.*, Hawkins, E., Harris, M. A., de Nooij, L., McIntosh, A. M., Wood, S. J., & Whalley, H. C. (2020). Aberrant structural covariance networks in youth at high familial risk for mood disorder. Bipolar Disorders 22(2), 155-162.
  1. Rupprechter, S., Romaniuk, L., Series, P., Hirose, Y., Hawkins, E., Sandu, A. L., Waiter, G. D., McNeil, C. J., Shen, X.*, . . . Steele, J. D. (2020). Blunted medial prefrontal cortico-limbic reward-related effective connectivity and depression. Brain 143(6), 1946-1956. https://doi.org/10.1093/brain/awaa106
  1. Stolicyn, A., Harris, M. A., Shen, X.*, Barbu, M. C., Adams, M. J., Hawkins, E. L., de Nooij, L., Yeung, H. W., Murray, A. D., . . . Lawrie, S. M. (2020). Automated classification of depression from structural brain measures across two independent community‐based cohorts. Human Brain Mapping 41(14), 3922-3937.
  1. van Velzen, L. S., Kelly, S., Isaev, D., Aleman, A., Aftanas, L. I., Bauer, J., Baune, B. T., Brak, I. V., Carballedo, A., . . . Schmaal, L. (2020). White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group. Mol Psychiatry 25(7), 1511-1525. https://doi.org/10.1038/s41380-019-0477-2
  1. Xu, P., Van Dam, N. T., van Tol, M.-J., Shen, X.*, Cui, Z., Gu, R., Qin, S., Aleman, A., Fan, J., . . . Luo, Y.-j. (2020). Amygdala–prefrontal connectivity modulates loss aversion bias in anxious individuals. Neuroimage 218, 116957.
  1. Barbu, M. C., Zeng, Y., Shen, X.*, Cox, S. R., Clarke, T.-K., Gibson, J., Adams, M. J., Johnstone, M., Haley, C. S., . . . Lawrie, S. M. (2019). Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 4(1), 91-100.
  1. Cox, S. R., Lyall, D. M., Ritchie, S. J., Bastin, M. E., Harris, M. A., Buchanan, C. R., Fawns-Ritchie, C., Barbu, M. C., De Nooij, L., . . . Reus, L. M. (2019). Associations between vascular risk factors and brain MRI indices in UK Biobank. European heart journal 40(28), 2290-2300.
  1. De Nooij, L., Harris, M. A., Hawkins, E. L., Clarke, T.-K., Shen, X.*, Chan, S. W., Ziermans, T. B., McIntosh, A. M., & Whalley, H. C. (2019). Longitudinal trajectories of brain age in young individuals at familial risk of mood disorder. Wellcome open research 4.
  1. Hill, W. D., Davies, N. M., Ritchie, S. J., Skene, N. G., Bryois, J., Bell, S., Di Angelantonio, E., Roberts, D. J., Xueyi, S., . . . Deary, I. J. (2019). Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income. Nat Commun 10(1), 5741. https://doi.org/10.1038/s41467-019-13585-5
  1. Howard, D. M., Adams, M. J., Clarke, T. K., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., . . . McIntosh, A. M. (2019). Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. Nat Neurosci 22(3), 343-352. https://doi.org/10.1038/s41593-018-0326-7
  1. Neilson, E., Shen, X.*, Cox, S. R., Clarke, T. K., Wigmore, E. M., Gibson, J., Howard, D. M., Adams, M. J., Harris, M. A., . . . Lawrie, S. M. (2019). Impact of Polygenic Risk for Schizophrenia on Cortical Structure in UK Biobank. Biol Psychiatry 86(7), 536-544. https://doi.org/10.1016/j.biopsych.2019.04.013
  1. Romaniuk, L., Sandu, A. L., Waiter, G. D., McNeil, C. J., Xueyi, S., Harris, M. A., Macfarlane, J. A., Lawrie, S. M., Deary, I. J., . . . Whalley, H. C. (2019). The Neurobiology of Personal Control During Reward Learning and Its Relationship to Mood. Biol Psychiatry Cogn Neurosci Neuroimaging 4(2), 190-199. https://doi.org/10.1016/j.bpsc.2018.09.015
  1. Romaniuk, L., Sandu, A.-L., Waiter, G. D., McNeil, C. J., Xueyi, S., Harris, M. A., Macfarlane, J. A., Lawrie, S. M., Deary, I. J., . . . Murray, A. D. (2019). The neurobiology of personal control during reward learning and its relationship to mood. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 4(2), 190-199.
  1. Zhu, R., Wu, H., Xu, Z., Tang, H., Shen, X.*, Mai, X., & Liu, C. (2019). Early distinction between shame and guilt processing in an interpersonal context. Social neuroscience 14(1), 53-66.
  1. Howard, D. M., Adams, M. J., Shirali, M., Clarke, T. K., Marioni, R. E., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X.*, . . . McIntosh, A. M. (2018). Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways. Nat Commun 9(1), 3578. https://doi.org/10.1038/s41467-018-05310-5
  1. Ritchie, S. J., Cox, S. R., Shen, X.*, Lombardo, M. V., Reus, L. M., Alloza, C., Harris, M. A., Alderson, H. L., Hunter, S., . . . Neilson, E. (2018). Sex differences in the adult human brain: evidence from 5216 UK biobank participants. Cerebral cortex 28(8), 2959-2975.
  1. Reus, L. M., Shen, X.*, Gibson, J., Wigmore, E., Ligthart, L., Adams, M. J., Davies, G., Cox, S. R., Hagenaars, S. P., . . . McIntosh, A. M. (2017). Association of polygenic risk for major psychiatric illness with subcortical volumes and white matter integrity in UK Biobank. Sci Rep 7, 42140. https://doi.org/10.1038/srep42140
  1. Zhu, R., Shen, X.*, Tang, H., Ye, P., Wang, H., Mai, X., & Liu, C. (2017). Self-punishment promotes forgiveness in the direct and indirect reciprocity contexts. Psychological reports 120(3), 408-422.
  1. Zhu, R., Jin, T., Shen, X.*, Zhang, S., Mai, X., & Liu, C. (2017). Relational utility affects self-punishment in direct and indirect reciprocity situations. Social Psychology 48(1), 19.
  1. Cullen, B., Nicholl, B. I., Mackay, D. F., Martin, D., Ul-Haq, Z., McIntosh, A., Gallacher, J., Deary, I. J., Pell, J. P., . . . Smith, D. J. (2015). Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants. Eur Psychiatry 30(8), 950-958. https://doi.org/10.1016/j.eurpsy.2015.08.006
  1. Zhu, R., Zhang, S., Shen, X.*, & Liu, C. (2014). Self-punishment: Contributing Factors, Theoretical Models and Research Prospects. Advances in Psychological Science 22(12), 1935.
  1. Feng, C., Luo, Y., Gu, R., Broster, L. S., Shen, X.*, Tian, T., Luo, Y.J., & Krueger, F. (2013). The flexible fairness: equality, earned entitlement, and self-interest. PLOS ONE, 8(9), e73106.
Conference abstracts and preprints (click here to see the full list)
  1. Davyson, E., Shen, X.*, Adams, M., Marioni, R., Barker, L., Wray, N., & McIntosh, A. (2023). 72. Methylome-Wide Association Study of Antidepressant Exposure. European Neuropsychopharmacology 75, S95.
  1. Han, L., Toenders, Y., Shen, X.*, Milaneschi, Y., Whalley, H., & Schmaal, L. (2023). The Brain Age Gap and Genetic Liability for Depression and Inflammation. Biological Psychiatry 93(9), S14.
  1. Moodie, J. E., Harris, S. E., Harris, M. A., Buchanan, C. R., Davies, G., Taylor, A., Redmond, P., Liewald, D., Del, C. V. H. M., . . . Cox, S. R. (2023). General and specific patterns of cortical gene expression as spatial correlates of complex cognitive functioning. bioRxiv. https://doi.org/10.1101/2023.03.16.532915
  1. Shen, C., Adams, M., Davyson, E., Iveson, M., McIntosh, A. M., & Shen, X.* (2023). The effects of CYP2C19 metaboliser status on DNA methylation. bioRxiv, 2023.2009.2007.555071. https://doi.org/10.1101/2023.09.07.555071
  1. Stolicyn, A., Harris, M. A., Nooij, L. d., Shen, X.*, Macfarlane, J. A., Campbell, A., McNeil, C. J., Sandu, A.-L., Murray, A. D., . . . Whalley, H. C. (2023). Disrupted Limbic-Prefrontal Effective Connectivity in Response to Fearful Faces in Lifetime Depression. medRxiv, 2023.2007.2018.23292846. https://doi.org/10.1101/2023.07.18.23292846
  1. Toenders, Y., Han, L., Shen, X.*, Pozzi, E., Whalley, H., Milaneschi, Y., Schmaal, L., & Consortium, E. M. (2023). Associations Between MDD Neurovegetative Subtypes, Structural Brain Alterations and Polygenic Risk Scores in Enigma-MDD. Biological Psychiatry 93(9), S14.
  1. Viejo-Romero, M., Whalley, H. C., Shen, X.*, Stolicyn, A., Nooij, L. d., Smith, D. J., & Howard, D. M. (2023). An epidemiological study of season of birth, mental health, and neuroimaging in the UK Biobank. medRxiv, 2023.2008.2009.23293866. https://doi.org/10.1101/2023.08.09.23293866
  1. Walker, R. M., Chong, M., Perrot, N., Pigeyre, M., Gadd, D. A., Stolicyn, A., Shi, L., Campbell, A., Shen, X.*, . . . Paré, G. (2023). The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses. medRxiv, 2023.2007.2027.23293236. https://doi.org/10.1101/2023.07.27.23293236
  1. Davyson, E., Shen, X.*, Adams, M., Marioni, R., & McIntosh, A. (2022). T57. A Metabolome-Wide Association Study of Major Depressive Disorder Indicates a Potential Causal Link To FADS1. European Neuropsychopharmacology 63, e199.
  1. Edmondson-Stait, A., Adams, M. J., Shen, X.*, Robert, C., McIntosh, A. M., Miron, V. E., Allardyce, J., Lawrie, S. M., & Whalley, H. C. (2022). Shared and Distinct Associations Between Inflammatory Markers and Major Psychiatric Disorders. European Neuropsychopharmacology 63, e255.
  1. Edmondson-Stait, A., Shen, X.*, Adams, M. J., Barbu, M. C., Jones, H. J., Miron, V. E., Allardyce, J., Lawrie, S. M., Khandaker, G. M., & McIntosh, A. M. (2022). T79. Associations Between Markers of Inflammation and Later Episodes if Depression and Psychotic Like Experiences From 10 To 28 Years Old. European Neuropsychopharmacology 63, e211.
  1. Shen, X.*, Choi, K., Lin, B., Adams, M., McIntosh, A., & Group, P.-M. W. (2022). A Phenome-Wide Mendelian Randomisation Study for Major Depressive Disorder. European Neuropsychopharmacology 63, e118-e119.
  1. Shen, X.*, Caramaschi, D., Adams, M., Walker, R., Min, J. L., Kwong, A., Barbu, M., Whalley, H., Harris, S., & Deary, I. J. (2021). DNA Methylome-Wide Association Study of Polygenic Risk Scores for Depression Implicating Antigen Processing and Immune Responses. European Neuropsychopharmacology 51, e14-e15.
  1. Barbu, M., Zeng, Y., Shen, X.*, Cox, S., Clarke, T.-K., Gibson, J., Adams, M., Johnstone, M., Haley, C. S., & Lawrie, S. (2019). SA81. Association of Whole-Genome And NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder And White Matter Microstructure in UK Biobank. European Neuropsychopharmacology 29, S1231-S1232.
  1. Harris, M., Shen, X.*, Cox, S., Gibson, J., Adams, M., Clarke, T., Deary, I. J., Lawrie, S., McIntosh, A., & Whalley, H. (2019). SU44. Stratifying Major Depressive Disorder by Polygenic Risk for Schizophrenia: Differences in Underlying Neurobiology. European Neuropsychopharmacology 29, S1291.
  1. McIntosh, A., Shen, X.*, Howard, D., Adams, M., Clarke, T., Whalley, H., Coleman, J., Wray, N., Lewis, C., & Sullivan, P. (2019). Uncovering the genetic architecture of major depression and its phenome-wide effects. European Neuropsychopharmacology 29, S52-S53.
  1. Neilson, E., Clarke, T., Shen, X.*, Cox, S., Shirali, M., Howard, D., Gibson, J., Adams, M., Harris, M., & Davies, G. (2019). Exploring the Relationship of Birth Weight on Cortical Brain Structure in UK Biobank Using Genetic Instruments. European Neuropsychopharmacology,
  1. Shen, X.*, Cox, S., Gibson, J., Adams, M., Howard, D., McIntosh, A., & Whalley, H. (2019). Resting State Functional Dynamics in Major Depressive Disorder and Relationship With Polygenic Risk Loading: Evidence From UK Biobank. European Neuropsychopharmacology 29, S907-S908.
  1. Shen, X.*, Gibson, J., Adams, M., Howard, D., McIntosh, A., & Whalley, H. (2019). F43. Polygenic Risk Of Major Depressive Disorder Is Associated With White Matter Microstructure: Evidence From UK Biobank Imaging Study Of 9,748 Participants. European Neuropsychopharmacology 29, S1132-S1133.
  1. Whalley, H., Harris, M., Shen, X.*, Gibson, J., Adams, M., Clarke, T., Lawrie, S., & McIntosh, A. (2019). 47. Associations of Polygenic Risk for Major Psychiatric Disorder With Brain Structure in Depression and Application to Stratification. Biological Psychiatry 85(10), S19-S20.
  1. Harris, M., Cox, S., Shen, X.*, Adams, M., Lawrie, S., Whalley, H., & McIntosh, A. (2018). S125. Different Definitions Reflect Neurobiologically Distinct Subtypes of Depression. Biological Psychiatry 83(9), S396.
  1. Whalley, H., Harris, M., Shen, X.*, Gibson, J., Lawrie, S., & McIntosh, A. (2018). S130. Dissecting the Neuroimaging Phenotype of Major Depressive Disorder Based on Genetic Loading for Schizophrenia. Biological Psychiatry 83(9), S398.