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A brief summary of myself
I am a researcher at the University of Edinburgh, where I utilize state-of-the-art statistical models to study Major Depressive Disorder. My expertise lies in the intersection of neuroscience and genomics, a field known as neuro-genomics. With a strong interest in mental health disorders, I believe it is crucial to combine these two disciplines to uncover the true mechanisms underlying depression.
In my research, I analyse large-scale clinical data to investigate the biological mechanisms of depression. This involves programming, data visualization, and writing research articles. I strongly believe in the power of data and figures, and I strive to conduct data-driven research.
Education
- 2015-2019: PhD in Psychiatry, University of Edinburgh, UK
- 2012-2015: MSc in Cognitive Neuroscience, Beijing Normal University, China
- 2008-2012: BSc in Psychology, South China Normal University, China
Work
- 2019-2023: Research Fellow, University of Edinburgh
- 2010-2010: On-campus counsellor, Zhaoqing High School, China
Publication
Number of first/corresponding author publications: 9
Total number of peer-reviewed publications: 54 (total citation = 3,910)
Research articles (click here to see the full list)
First/corresponding-author publications:
- Shen, X.*, Caramaschi, D., Adams, M. J., Walker, R. M., Min, J. L., Kwong, A., Hemani, G., Consortium, G. o. D. M., Barbu, M. C., . . . Whalley, H. C. (2022). DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses. Genome Medicine 14(1), 36.
- Thng, G., Shen, X.* (corresponding author), Stolicyn, A., Harris, M. A., Adams, M. J., Barbu, M. C., Kwong, A. S., Frangou, S., Lawrie, S. M., . . . McIntosh, A. M. (2022). Comparing personalized brain-based and genetic risk scores for major depressive disorder in large population samples of adults and adolescents. European Psychiatry 65(1), e44.
- Shen, X.*, MacSweeney, N., Chan, S. W., Barbu, M. C., Adams, M. J., Lawrie, S. M., Romaniuk, L., McIntosh, A. M., & Whalley, H. C. (2021). Brain structural associations with depression in a large early adolescent sample (the ABCD study®). EClinicalMedicine 42.
- Shen, X.*, Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T.-K., Deary, I. J., Whalley, H. C., & McIntosh, A. M. (2020). A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank. Nature Communications 11(1), 2301.
- Shen, X.*, Adams, M. J., Ritakari, T. E., Cox, S. R., McIntosh, A. M., & Whalley, H. C. (2019). White matter microstructure and its relation to longitudinal measures of depressive symptoms in mid-and late life. Biological Psychiatry 86(10), 759-768.
- Shen, X.*, Cox, S. R., Adams, M. J., Howard, D. M., Lawrie, S. M., Ritchie, S. J., Bastin, M. E., Deary, I. J., McIntosh, A. M., . . . Whalley, H. C. (2018). Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 3(10), 878-886.
- Shen, X.*, Reus, L. M., Cox, S. R., Adams, M. J., Liewald, D. C., Bastin, M. E., Smith, D. J., Deary, I. J., Whalley, H. C., . . . McIntosh, A. M. (2017). Subcortical volume and white matter integrity abnormalities in major depressive disorder: findings from UK Biobank imaging data. Scientific reports 7(1), 5547.
- Zhu, R., Shen, X.*, Tang, H., Ye, P., Wang, H., Mai, X., & Liu, C. (2017). Self-punishment promotes forgiveness in the direct and indirect reciprocity contexts. Psychological reports 120(3), 408-422.
- Shen, X.*, Mai, X., & Liu, C. (2015). Application of Internetbased big data in social cognitive science. Chinese Science Bulletin 60(11), 986-987.
Other peer-reviewed publications
- Bosma, M., Cox, S., Ziermans, T., Buchanan, C., Shen, X.*, Tucker-Drob, E., Adams, M., Whalley, H., & Lawrie, S. (2023). White matter, cognition and psychotic-like experiences in UK Biobank. Psychological Medicine 53(6), 2370-2379.
- Cullen, B., Gameroff, M. J., Ward, J., Bailey, M. E. S., Lyall, D. M., Lyall, L. M., MacSweeney, N., Murphy, E., Sangha, N., . . . Weissman, M. M. (2023). Cognitive Function in People With Familial Risk of Depression. JAMA Psychiatry 80(6), 610-620. https://doi.org/10.1001/jamapsychiatry.2023.0716
- Davyson, E., Shen, X.*, Gadd, D. A., Bernabeu, E., Hillary, R. F., McCartney, D. L., Adams, M., Marioni, R., & McIntosh, A. M. (2023). Metabolomic investigation of major depressive disorder identifies a potentially causal association with polyunsaturated fatty acids. Biological Psychiatry.
- Gao, C., Amador, C., Walker, R. M., Campbell, A., Madden, R. A., Adams, M. J., Bai, X., Liu, Y., Li, M., . . . Zeng, Y. (2023). Phenome-wide analyses identify an association between the parent-of-origin effects dependent methylome and the rate of aging in humans. Genome Biol 24(1), 117. https://doi.org/10.1186/s13059-023-02953-6
- MacSweeney, N., Allardyce, J., Edmondson-Stait, A., Shen, X.*, Casey, H., Chan, S. W. Y., Cullen, B., Reynolds, R. M., Frangou, S., . . . Whalley, H. C. (2023). The role of brain structure in the association between pubertal timing and depression risk in an early adolescent sample (the ABCD Study(R)): A registered report. Dev Cogn Neurosci 60, 101223. https://doi.org/10.1016/j.dcn.2023.101223
- Madden, R. A., Atkinson, K., Shen, X.*, Green, C., Hillary, R. F., Hawkins, E., Sage, E., Sandu, A. L., Waiter, G., . . . Whalley, H. C. (2023). Structural brain correlates of childhood trauma with replication across two large, independent community-based samples. Eur Psychiatry 66(1), e19. https://doi.org/10.1192/j.eurpsy.2022.2347
- Stolicyn, A., Lyall, L. M., Lyall, D. M., Høier, N., Adams, M. J., Shen, X., Cole, J. H., McIntosh, A. M., Whalley, H. C., . . . Smith, D. J. (in press). Comprehensive Assessment of Sleep Duration, Insomnia and Brain Structure within the UK Biobank Cohort. Sleep, preprint available at: https://doi.org/10.1101/2023.06.19.23291496
- Barbu, M. C., Harris, M., Shen, X.*, Aleks, S., Green, C., Amador, C., Walker, R., Morris, S., Adams, M., . . . Whalley, H. (2022). Epigenome-wide association study of global cortical volumes in generation Scotland: Scottish family health study. Epigenetics 17(10), 1143-1158. https://doi.org/10.1080/15592294.2021.1997404
- Barbu, M. C., Amador, C., Kwong, A. S. F., Shen, X.*, Adams, M. J., Howard, D. M., Walker, R. M., Morris, S. W., Min, J. L., . . . McIntosh, A. M. (2022). Complex trait methylation scores in the prediction of major depressive disorder. eBioMedicine 79, 104000. https://doi.org/10.1016/j.ebiom.2022.104000
- Edmondson-Stait, A. J., Shen, X.*, Adams, M. J., Barbu, M. C., Jones, H. J., Miron, V. E., Allardyce, J., Boardman, J. P., Lawrie, S. M., . . . McIntosh, A. M. (2022). Early-life inflammatory markers and subsequent psychotic and depressive episodes between 10 to 28 years of age. Brain, Behavior, & Immunity-Health 26, 100528.
- Gadd, D. A., Hillary, R. F., McCartney, D. L., Shi, L., Stolicyn, A., Robertson, N. A., Walker, R. M., McGeachan, R. I., Campbell, A., . . . Marioni, R. E. (2022). Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health. Nat Commun 13(1), 4670. https://doi.org/10.1038/s41467-022-32319-8
- Harris, M. A., Cox, S. R., De Nooij, L., Barbu, M. C., Adams, M. J., Shen, X.*, Deary, I. J., Lawrie, S. M., McIntosh, A. M., . . . Whalley, H. C. (2022). Structural neuroimaging measures and lifetime depression across levels of phenotyping in UK biobank. Translational Psychiatry 12(1), 157.
- Yeung, H., Shen, X.*, Stolicyn, A., de Nooij, L., Harris, M., Romaniuk, L., Buchanan, C., Waiter, G., Sandu, A.-L., . . . McNeil, C. (2022). Spectral clustering based on structural magnetic resonance imaging and its relationship with major depressive disorder and cognitive ability (vol 54, pg 6281, 2021). EUROPEAN JOURNAL OF NEUROSCIENCE 56(5), 4700-4700.
- Barbu, M. C., Shen, X.*, Walker, R. M., Howard, D. M., Evans, K. L., Whalley, H. C., Porteous, D. J., Morris, S. W., Deary, I. J., . . . Zeng, Y. (2021). Epigenetic prediction of major depressive disorder. Molecular Psychiatry 26(9), 5112-5123.
- Green, C., Stolicyn, A., Harris, M. A., Shen, X.*, Romaniuk, L., Barbu, M. C., Hawkins, E. L., Wardlaw, J. M., Steele, J. D., . . . Waiter, G. D. (2021). Hair glucocorticoids are associated with childhood adversity, depressive symptoms and reduced global and lobar grey matter in Generation Scotland. Translational Psychiatry 11(1), 523.
- Green, C., Shen, X.*, Stevenson, A. J., Conole, E. L., Harris, M. A., Barbu, M. C., Hawkins, E. L., Adams, M. J., Hillary, R. F., . . . Lawrie, S. M. (2021). Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder. Brain, behavior, and immunity 92, 39-48.
- Howard, D. M., Adams, M. J., Shirali, M., Clarke, T.-K., Marioni, R. E., Davies, G., Coleman, J. R., Alloza, C., Shen, X.*, . . . Barbu, M. C. (2021). Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways (vol 9, 1470, 2018). Nature Communications 12(1).
- Schoorl, J., Barbu, M. C., Shen, X.*, Harris, M. R., Adams, M. J., Whalley, H. C., & Lawrie, S. M. (2021). Grey and white matter associations of psychotic-like experiences in a general population sample (UK Biobank). Translational Psychiatry 11(1), 21.
- Sewell, M. D., Jiménez-Sánchez, L., Shen, X.*, Edmondson-Stait, A. J., Green, C., Adams, M. J., Rifai, O. M., McIntosh, A. M., Lyall, D. M., . . . Whalley, H. C. (2021). Associations between major psychiatric disorder polygenic risk scores and blood-based markers in UK biobank. Brain, behavior, and immunity 97, 32-41.
- Yeung, H. W., Shen, X.*, Stolicyn, A., De Nooij, L., Harris, M. A., Romaniuk, L., Buchanan, C. R., Waiter, G. D., Sandu, A. L., . . . McNeil, C. J. (2021). Spectral clustering based on structural magnetic resonance imaging and its relationship with major depressive disorder and cognitive ability. EUROPEAN JOURNAL OF NEUROSCIENCE 54(6), 6281-6303.
- Barbu, M. C., Spiliopoulou, A., Colombo, M., McKeigue, P., Clarke, T.-K., Howard, D. M., Adams, M. J., Shen, X.*, Lawrie, S. M., . . . McIntosh, A. M. (2020). Expression quantitative trait loci-derived scores and white matter microstructure in UK Biobank: a novel approach to integrating genetics and neuroimaging. Translational Psychiatry 10(1), 55.
- de Nooij, L., Harris, M. A., Adams, M. J., Clarke, T.-K., Shen, X.*, Cox, S. R., McIntosh, A. M., & Whalley, H. C. (2020). Cognitive functioning and lifetime major depressive disorder in UK Biobank. European Psychiatry 63(1), e28.
- Harris, M. A., Shen, X.*, Cox, S. R., Gibson, J., Adams, M. J., Clarke, T.-K., Deary, I. J., Lawrie, S. M., McIntosh, A. M., . . . Whalley, H. C. (2020). Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures. Psychological Medicine 50(10), 1653-1662.
- Heinze, K., Shen, X.*, Hawkins, E., Harris, M. A., de Nooij, L., McIntosh, A. M., Wood, S. J., & Whalley, H. C. (2020). Aberrant structural covariance networks in youth at high familial risk for mood disorder. Bipolar Disorders 22(2), 155-162.
- Rupprechter, S., Romaniuk, L., Series, P., Hirose, Y., Hawkins, E., Sandu, A. L., Waiter, G. D., McNeil, C. J., Shen, X.*, . . . Steele, J. D. (2020). Blunted medial prefrontal cortico-limbic reward-related effective connectivity and depression. Brain 143(6), 1946-1956. https://doi.org/10.1093/brain/awaa106
- Stolicyn, A., Harris, M. A., Shen, X.*, Barbu, M. C., Adams, M. J., Hawkins, E. L., de Nooij, L., Yeung, H. W., Murray, A. D., . . . Lawrie, S. M. (2020). Automated classification of depression from structural brain measures across two independent community‐based cohorts. Human Brain Mapping 41(14), 3922-3937.
- van Velzen, L. S., Kelly, S., Isaev, D., Aleman, A., Aftanas, L. I., Bauer, J., Baune, B. T., Brak, I. V., Carballedo, A., . . . Schmaal, L. (2020). White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group. Mol Psychiatry 25(7), 1511-1525. https://doi.org/10.1038/s41380-019-0477-2
- Xu, P., Van Dam, N. T., van Tol, M.-J., Shen, X.*, Cui, Z., Gu, R., Qin, S., Aleman, A., Fan, J., . . . Luo, Y.-j. (2020). Amygdala–prefrontal connectivity modulates loss aversion bias in anxious individuals. Neuroimage 218, 116957.
- Barbu, M. C., Zeng, Y., Shen, X.*, Cox, S. R., Clarke, T.-K., Gibson, J., Adams, M. J., Johnstone, M., Haley, C. S., . . . Lawrie, S. M. (2019). Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 4(1), 91-100.
- Cox, S. R., Lyall, D. M., Ritchie, S. J., Bastin, M. E., Harris, M. A., Buchanan, C. R., Fawns-Ritchie, C., Barbu, M. C., De Nooij, L., . . . Reus, L. M. (2019). Associations between vascular risk factors and brain MRI indices in UK Biobank. European heart journal 40(28), 2290-2300.
- De Nooij, L., Harris, M. A., Hawkins, E. L., Clarke, T.-K., Shen, X.*, Chan, S. W., Ziermans, T. B., McIntosh, A. M., & Whalley, H. C. (2019). Longitudinal trajectories of brain age in young individuals at familial risk of mood disorder. Wellcome open research 4.
- Hill, W. D., Davies, N. M., Ritchie, S. J., Skene, N. G., Bryois, J., Bell, S., Di Angelantonio, E., Roberts, D. J., Xueyi, S., . . . Deary, I. J. (2019). Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income. Nat Commun 10(1), 5741. https://doi.org/10.1038/s41467-019-13585-5
- Howard, D. M., Adams, M. J., Clarke, T. K., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., . . . McIntosh, A. M. (2019). Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. Nat Neurosci 22(3), 343-352. https://doi.org/10.1038/s41593-018-0326-7
- Neilson, E., Shen, X.*, Cox, S. R., Clarke, T. K., Wigmore, E. M., Gibson, J., Howard, D. M., Adams, M. J., Harris, M. A., . . . Lawrie, S. M. (2019). Impact of Polygenic Risk for Schizophrenia on Cortical Structure in UK Biobank. Biol Psychiatry 86(7), 536-544. https://doi.org/10.1016/j.biopsych.2019.04.013
- Romaniuk, L., Sandu, A. L., Waiter, G. D., McNeil, C. J., Xueyi, S., Harris, M. A., Macfarlane, J. A., Lawrie, S. M., Deary, I. J., . . . Whalley, H. C. (2019). The Neurobiology of Personal Control During Reward Learning and Its Relationship to Mood. Biol Psychiatry Cogn Neurosci Neuroimaging 4(2), 190-199. https://doi.org/10.1016/j.bpsc.2018.09.015
- Romaniuk, L., Sandu, A.-L., Waiter, G. D., McNeil, C. J., Xueyi, S., Harris, M. A., Macfarlane, J. A., Lawrie, S. M., Deary, I. J., . . . Murray, A. D. (2019). The neurobiology of personal control during reward learning and its relationship to mood. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 4(2), 190-199.
- Zhu, R., Wu, H., Xu, Z., Tang, H., Shen, X.*, Mai, X., & Liu, C. (2019). Early distinction between shame and guilt processing in an interpersonal context. Social neuroscience 14(1), 53-66.
- Howard, D. M., Adams, M. J., Shirali, M., Clarke, T. K., Marioni, R. E., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X.*, . . . McIntosh, A. M. (2018). Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways. Nat Commun 9(1), 3578. https://doi.org/10.1038/s41467-018-05310-5
- Ritchie, S. J., Cox, S. R., Shen, X.*, Lombardo, M. V., Reus, L. M., Alloza, C., Harris, M. A., Alderson, H. L., Hunter, S., . . . Neilson, E. (2018). Sex differences in the adult human brain: evidence from 5216 UK biobank participants. Cerebral cortex 28(8), 2959-2975.
- Reus, L. M., Shen, X.*, Gibson, J., Wigmore, E., Ligthart, L., Adams, M. J., Davies, G., Cox, S. R., Hagenaars, S. P., . . . McIntosh, A. M. (2017). Association of polygenic risk for major psychiatric illness with subcortical volumes and white matter integrity in UK Biobank. Sci Rep 7, 42140. https://doi.org/10.1038/srep42140
- Zhu, R., Shen, X.*, Tang, H., Ye, P., Wang, H., Mai, X., & Liu, C. (2017). Self-punishment promotes forgiveness in the direct and indirect reciprocity contexts. Psychological reports 120(3), 408-422.
- Zhu, R., Jin, T., Shen, X.*, Zhang, S., Mai, X., & Liu, C. (2017). Relational utility affects self-punishment in direct and indirect reciprocity situations. Social Psychology 48(1), 19.
- Cullen, B., Nicholl, B. I., Mackay, D. F., Martin, D., Ul-Haq, Z., McIntosh, A., Gallacher, J., Deary, I. J., Pell, J. P., . . . Smith, D. J. (2015). Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants. Eur Psychiatry 30(8), 950-958. https://doi.org/10.1016/j.eurpsy.2015.08.006
- Zhu, R., Zhang, S., Shen, X.*, & Liu, C. (2014). Self-punishment: Contributing Factors, Theoretical Models and Research Prospects. Advances in Psychological Science 22(12), 1935.
- Feng, C., Luo, Y., Gu, R., Broster, L. S., Shen, X.*, Tian, T., Luo, Y.J., & Krueger, F. (2013). The flexible fairness: equality, earned entitlement, and self-interest. PLOS ONE, 8(9), e73106.
Conference abstracts and preprints (click here to see the full list)
- Davyson, E., Shen, X.*, Adams, M., Marioni, R., Barker, L., Wray, N., & McIntosh, A. (2023). 72. Methylome-Wide Association Study of Antidepressant Exposure. European Neuropsychopharmacology 75, S95.
- Han, L., Toenders, Y., Shen, X.*, Milaneschi, Y., Whalley, H., & Schmaal, L. (2023). The Brain Age Gap and Genetic Liability for Depression and Inflammation. Biological Psychiatry 93(9), S14.
- Moodie, J. E., Harris, S. E., Harris, M. A., Buchanan, C. R., Davies, G., Taylor, A., Redmond, P., Liewald, D., Del, C. V. H. M., . . . Cox, S. R. (2023). General and specific patterns of cortical gene expression as spatial correlates of complex cognitive functioning. bioRxiv. https://doi.org/10.1101/2023.03.16.532915
- Shen, C., Adams, M., Davyson, E., Iveson, M., McIntosh, A. M., & Shen, X.* (2023). The effects of CYP2C19 metaboliser status on DNA methylation. bioRxiv, 2023.2009.2007.555071. https://doi.org/10.1101/2023.09.07.555071
- Stolicyn, A., Harris, M. A., Nooij, L. d., Shen, X.*, Macfarlane, J. A., Campbell, A., McNeil, C. J., Sandu, A.-L., Murray, A. D., . . . Whalley, H. C. (2023). Disrupted Limbic-Prefrontal Effective Connectivity in Response to Fearful Faces in Lifetime Depression. medRxiv, 2023.2007.2018.23292846. https://doi.org/10.1101/2023.07.18.23292846
- Toenders, Y., Han, L., Shen, X.*, Pozzi, E., Whalley, H., Milaneschi, Y., Schmaal, L., & Consortium, E. M. (2023). Associations Between MDD Neurovegetative Subtypes, Structural Brain Alterations and Polygenic Risk Scores in Enigma-MDD. Biological Psychiatry 93(9), S14.
- Viejo-Romero, M., Whalley, H. C., Shen, X.*, Stolicyn, A., Nooij, L. d., Smith, D. J., & Howard, D. M. (2023). An epidemiological study of season of birth, mental health, and neuroimaging in the UK Biobank. medRxiv, 2023.2008.2009.23293866. https://doi.org/10.1101/2023.08.09.23293866
- Walker, R. M., Chong, M., Perrot, N., Pigeyre, M., Gadd, D. A., Stolicyn, A., Shi, L., Campbell, A., Shen, X.*, . . . Paré, G. (2023). The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses. medRxiv, 2023.2007.2027.23293236. https://doi.org/10.1101/2023.07.27.23293236
- Davyson, E., Shen, X.*, Adams, M., Marioni, R., & McIntosh, A. (2022). T57. A Metabolome-Wide Association Study of Major Depressive Disorder Indicates a Potential Causal Link To FADS1. European Neuropsychopharmacology 63, e199.
- Edmondson-Stait, A., Adams, M. J., Shen, X.*, Robert, C., McIntosh, A. M., Miron, V. E., Allardyce, J., Lawrie, S. M., & Whalley, H. C. (2022). Shared and Distinct Associations Between Inflammatory Markers and Major Psychiatric Disorders. European Neuropsychopharmacology 63, e255.
- Edmondson-Stait, A., Shen, X.*, Adams, M. J., Barbu, M. C., Jones, H. J., Miron, V. E., Allardyce, J., Lawrie, S. M., Khandaker, G. M., & McIntosh, A. M. (2022). T79. Associations Between Markers of Inflammation and Later Episodes if Depression and Psychotic Like Experiences From 10 To 28 Years Old. European Neuropsychopharmacology 63, e211.
- Shen, X.*, Choi, K., Lin, B., Adams, M., McIntosh, A., & Group, P.-M. W. (2022). A Phenome-Wide Mendelian Randomisation Study for Major Depressive Disorder. European Neuropsychopharmacology 63, e118-e119.
- Shen, X.*, Caramaschi, D., Adams, M., Walker, R., Min, J. L., Kwong, A., Barbu, M., Whalley, H., Harris, S., & Deary, I. J. (2021). DNA Methylome-Wide Association Study of Polygenic Risk Scores for Depression Implicating Antigen Processing and Immune Responses. European Neuropsychopharmacology 51, e14-e15.
- Barbu, M., Zeng, Y., Shen, X.*, Cox, S., Clarke, T.-K., Gibson, J., Adams, M., Johnstone, M., Haley, C. S., & Lawrie, S. (2019). SA81. Association of Whole-Genome And NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder And White Matter Microstructure in UK Biobank. European Neuropsychopharmacology 29, S1231-S1232.
- Harris, M., Shen, X.*, Cox, S., Gibson, J., Adams, M., Clarke, T., Deary, I. J., Lawrie, S., McIntosh, A., & Whalley, H. (2019). SU44. Stratifying Major Depressive Disorder by Polygenic Risk for Schizophrenia: Differences in Underlying Neurobiology. European Neuropsychopharmacology 29, S1291.
- McIntosh, A., Shen, X.*, Howard, D., Adams, M., Clarke, T., Whalley, H., Coleman, J., Wray, N., Lewis, C., & Sullivan, P. (2019). Uncovering the genetic architecture of major depression and its phenome-wide effects. European Neuropsychopharmacology 29, S52-S53.
- Neilson, E., Clarke, T., Shen, X.*, Cox, S., Shirali, M., Howard, D., Gibson, J., Adams, M., Harris, M., & Davies, G. (2019). Exploring the Relationship of Birth Weight on Cortical Brain Structure in UK Biobank Using Genetic Instruments. European Neuropsychopharmacology,
- Shen, X.*, Cox, S., Gibson, J., Adams, M., Howard, D., McIntosh, A., & Whalley, H. (2019). Resting State Functional Dynamics in Major Depressive Disorder and Relationship With Polygenic Risk Loading: Evidence From UK Biobank. European Neuropsychopharmacology 29, S907-S908.
- Shen, X.*, Gibson, J., Adams, M., Howard, D., McIntosh, A., & Whalley, H. (2019). F43. Polygenic Risk Of Major Depressive Disorder Is Associated With White Matter Microstructure: Evidence From UK Biobank Imaging Study Of 9,748 Participants. European Neuropsychopharmacology 29, S1132-S1133.
- Whalley, H., Harris, M., Shen, X.*, Gibson, J., Adams, M., Clarke, T., Lawrie, S., & McIntosh, A. (2019). 47. Associations of Polygenic Risk for Major Psychiatric Disorder With Brain Structure in Depression and Application to Stratification. Biological Psychiatry 85(10), S19-S20.
- Harris, M., Cox, S., Shen, X.*, Adams, M., Lawrie, S., Whalley, H., & McIntosh, A. (2018). S125. Different Definitions Reflect Neurobiologically Distinct Subtypes of Depression. Biological Psychiatry 83(9), S396.
- Whalley, H., Harris, M., Shen, X.*, Gibson, J., Lawrie, S., & McIntosh, A. (2018). S130. Dissecting the Neuroimaging Phenotype of Major Depressive Disorder Based on Genetic Loading for Schizophrenia. Biological Psychiatry 83(9), S398.
- 作者:Xueyi Shen
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